Clinical efficacy of regional citrate anticoagulation in continuous renal replacement therapy: systematic review and meta-analysis
نویسندگان
چکیده
Background: A systematic review and meta-analysis were conducted to explore the clinical efficacy coagulation function of regional citrate anticoagulation (RCA) in continuous renal replacement therapy (CRRT) critically ill patients, provide an effective treatment options for CRRT severe patients.
منابع مشابه
Citrate anticoagulation for continuous renal replacement therapy
Clinical Problem A 73 year old female patient presented to the Accident and Emergency Department (A&E) with a profound anaemia, acute kidney injury (AKI) and severe hyperkalaemia. She had a background of Chronic Obstructive Pulmonary Disease (COPD), osteoarthritis, hypertension, morbid obesity and a very poor functional status. She described a one week history of bleeding haemorrhoids. She was ...
متن کاملClinical review: Anticoagulation for continuous renal replacement therapy - heparin or citrate?
Heparin is the most commonly prescribed anticoagulant for continuous renal replacement therapy. There is, however, increasing evidence questioning its safety, particularly in the critically ill. Heparin mainly confers its anticoagulant effect by binding to antithrombin. Heparin binds to numerous other proteins and cells as well, however, compromising its efficacy and safety. Owing to antithromb...
متن کاملIonized Magnesium and Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy
Background: The regional citrate anticoagulation (RCA) induces changes in total (Ca tot ) and ionized (Ca 2+ ) calcium. As of now, we do not have much information about parallel changes of total (Mg tot ) and ionized (Mg 2+ ) magnesium. Methods: The authors compared changes of Mg 2+ and Mg tot with changes of Ca 2+ and Ca tot in 32 critically ill patients on 4% trisodium citrate (4% TSC) with c...
متن کاملIonized Magnesium and Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy.
BACKGROUND The regional citrate anticoagulation (RCA) induces changes in total (Catot) and ionized (Ca2+) calcium. As of now, we do not have much information about parallel changes of total (Mgtot) and ionized (Mg2+) magnesium. METHODS The authors compared changes of Mg2+ and Mgtot with changes of Ca2+ and Catot in 32 critically ill patients on 4% trisodium citrate (4% TSC) with calcium-free ...
متن کاملRegional citrate anticoagulation for continuous renal replacement therapy in pediatric patients with liver failure
Pediatric liver failure patients frequently develop multiple organ failure and require continuous renal replacement therapy (CRRT) as part of supportive therapy in the pediatric intensive care unit. While many centers employ no anticoagulation for fear of bleeding complications, balanced coagulation disturbance predisposes these patients to clotting as well as bleeding, making maintenance of lo...
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ژورنال
عنوان ژورنال: Annals of palliative medicine
سال: 2021
ISSN: ['2224-5839', '2224-5820']
DOI: https://doi.org/10.21037/apm-21-1693